Description
Product Characteristics:
Aliases: EC 2.5.1.56 antibody, EC 2.5.1.57 antibody, N acetylneuraminate 9 phosphate synthase antibody, N acetylneuraminate synthase antibody, N acetylneuraminic acid phosphate synthase antibody, N acetylneuraminic acid synthase antibody, N-acetylneuraminate synthase antibody, N-acetylneuraminate-9-phosphate synthase antibody, N-acetylneuraminic acid phosphate synthase antibody, N-acetylneuraminic acid synthase antibody, NANS antibody, OTTHUMP00000021769 antibody, SAS antibody, Sialic acid phosphate synthase antibody, Sialic acid synthase antibody, SIAS_HUMAN antibody
Target Information: This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively\, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq, Jul 2008]